Treatment failure in a typhoid patient infected with nalidixic acid resistant S. enterica serovar Typhi with reduced susceptibility to Ciprofloxacin: a case report from Cameroon

Multidrug-resistant Salmonella enterica serovar typhi isolates with high-level resistance to ciprofloxacin in Dhaka, Bangladesh.

Typhoid fever due to multidrug-resistant Salmonella enterica serovar Typhi is a global public health problem, with an estimated 30 million cases and 600,000 deaths annually (7). Since the beginning of the 1990s, there has been an increasing prevalence of multidrug resistance to the first-line antimicrobials, such as chloramphenicol, ampicillin, and co-trimoxazole, shifting the drug of choice fo...

Nalidixic acid-resistant Salmonella enterica serovar Typhi with decreased susceptibility to ciprofloxacin caused treatment failure: a report from Bangladesh.

Multidrug resistant Salmonella enterica serovar typhi.

Nepal is having a series of enteric fever epidemics over the last decade1,2 with changing resistance patterns.3 The fi rst report of multidrug resistant Salmonella enterica serovar Typhi in Nepal was published in 1991.4 In the following years, with the introduction of fl uoroquinolones in the treatment, nalidixic acid-resistant strains associated with reduced susceptibility to fl oroquinolones ...

Current fluoroquinolone susceptibility criteria for Salmonella needs re-evaluation.

BACKGROUND Disc diffusion technique is the routine susceptibility testing procedure for isolates of enteric fever, the most common clinical diagnosis among febrile patients in Nepal. OBJECTIVE To evaluated the current fluoroquinolones (FQs) susceptibility criteria and nalidixic acid screening test in Salmonella enterica serovar Typhi and Paratyphi A. METHODS S. Typhi and Paratyphi A strains...

Antimicrobial Susceptibility Patterns of Salmonella enterica Serotype Typhi in Eastern Nepal

The aim of the present study was to evaluate antimicrobial susceptibility patterns with special reference to multidrug resistance, susceptibility to ciprofloxacin, and bacteriophage typing of Salmonella enterica serotype Typhi isolated from blood sent for culture in a tertiary-care teaching hospital in eastern Nepal during January 2000-December 2004. In total, 132 strains of S. enterica Typhi, ...